The Next Era of Beauty Science: Activating the Skin’s Natural “Factory”

In the relentless pursuit of actives that are both highly effective and profoundly compatible with Asian skin, Cosmosciene® is proud to introduce a revolutionary breakthrough from French dermatological biotechnology: PANTODIUM® CICA. This is not merely another ingredient; it is a paradigm shift that activates the skin to intelligently synthesize its own Vitamin B5 (Panthenol).

This launch embodies our core values: grounded in Science, driven by Innovation, and created for Humanity. It marks a pivotal moment in the future of skincare—a future where technology serves biology by awakening the skin’s innate intelligence.

Skinbiotech: A Revolution from Within

A Groundbreaking Mechanism of Action

Developed by the visionary team at Codif Laboratories, PANTODIUM® CICA transcends the limitations of traditional Vitamin B5 derivatives. It functions as a “microbial factory” on the skin’s surface, stimulating the native microbiota to produce bio-identical Panthenol precisely when and where it is needed, based on the skin’s unique condition.

This represents a quantum leap in personalized and bio-compatible skincare. It empowers the skin to self-regulate and regenerate, moving from a passive recipient of external ingredients to an active participant in its own healing journey. This is the essence of biological intelligence in cosmetics.

The “Less is More” Philosophy in Beauty Science

Instead of layering more substances onto the skin, PANTODIUM® CICA champions a more sophisticated approach: activating the skin’s inherent potential. This technology honors the skin’s microbiome, a complex and delicate ecosystem whose critical role in skin health is now a central focus of advanced dermatological science.

Superior Performance: Where Science Meets Innovation

Clinically Proven, Multi-Faceted Efficacy

PANTODIUM® CICA delivers a comprehensive profile of clinically validated benefits, directly addressing the core needs of modern skincare formulation:

• Robust Barrier Restoration: By facilitating the on-site synthesis of Panthenol, this active enhances the skin’s natural moisturizing factors and reinforces the critical lipid barrier, improving resilience against environmental stressors.
• Anti-Inflammatory & Balancing Action: The microbiome-mediated mechanism naturally modulates inflammatory responses, providing a profound soothing and calming effect for sensitized or reactive skin.
• Acne and Post-Inflammatory Hyperpigmentation (PIH) Support: By promoting a balanced microbiome and accelerating cellular turnover, it helps mitigate acne conditions and supports the fading of resultant dark spots.
• Advanced Scar and Trauma Recovery: The localized production of Panthenol creates an optimal micro-environment for tissue repair, accelerating the healing process for scars, burns, and post-procedure skin.

Practical Application: From Lab to Formulation

Recommended Concentration Guidelines

To support formulators in harnessing the full potential of this technology, we recommend the following usage levels:

• 0.5–1% for Daily Care: Ideal for daily moisturizers targeting dry, sensitive, or sun-exposed skin. At this concentration, PANTODIUM® CICA acts as a gentle activator, maintaining microbiome harmony and barrier integrity.
• 1% for Specialized Treatments: Perfectly suited for targeted treatments for acne-prone skin or post-procedure care. This level provides a significant boost to the skin’s regenerative processes while maintaining an excellent safety profile.
• 2% for Intensive Repair Balms: The recommended concentration for high-performance repair balms designed for scar treatment, burn recovery, and other forms of significant skin trauma.

The Cosmosciene® Vision: The Future of Intelligent Beauty

A Commitment to Sustainable, Human-Centric Solutions

PANTODIUM® CICA is a powerful demonstration of the Cosmosciene® vision. We believe the future of beauty lies not in overwhelming the skin, but in activating its innate power to heal and harmonize with its biological environment. It is the perfect convergence of Science, biology, and cosmetics delivering sustainable, smart, and human-centric solutions.

An Ecosystem Approach to Skincare

This ingredient moves beyond the “one-size-fits-all” model. It represents an ecosystem approach, where each individual’s skin is empowered to find its own optimal balance. This is the new definition of personalized skincare in the age of biotechnology, reflecting our mission to build intelligent and sustainable beauty ecosystems.

Conclusion: Science in Service of Humanity

PANTODIUM® CICA is more than an ingredient; it is proof of our foundational philosophy: true Science must serve Humanity in a way that is intelligent, sustainable, and respectful.

By understanding and collaborating with the skin’s natural biology, we unlock the next frontier of beauty science—a frontier where technology and nature work in synergy to create truly transformative results.